Royal Air Force Typhoon jets have operated alongside French aircraft in a combined operation on an subterranean weapons facility in Syrian territory used by the Islamic State group (IS), as stated by the UK's MoD.
The site, identified by surveillance, was believed to be storing arms and explosives, the announcement noted, and was positioned in hills just above the ancient city of Palmyra in the heart of Syria.
"Our aircraft employed precision-guided Paveway IV munitions to target a several approach shafts providing entry to the facility... early reports indicate the strike was effective," officials stated.
There was no sign of any harm to civilians in the attack on Saturday evening and all the aircraft made a safe return, the ministry further stated.
The British jets were assisted by a Voyager refuelling tanker.
The Islamic State group - also known as Daesh - imposed jihadist rule over large swathes of Syria and Iraq before its territorial defeat in 2019.
"This strike underscores British leadership, and resolve to operate in unison with our partners, to eliminate any resurgence of IS and their dangerous and violent ideologies in the Middle East," UK Defence Secretary the Defence Secretary said.
British military aircraft have performed overwatch operations over Syrian airspace to "deter any efforts to regroup" of the group subsequent to its routing at the battle of Baghuz in the year 2019, the MoD reported.
"I must thank all the members of the UK armed forces involved in this operation for their professionalism and their bravery," the Defence Secretary said. "Including them were thousands of UK service members stationed over the festive period. This action, to eliminate militants who endanger our safety, demonstrates how British military are prepared to act, continuously, protecting the UK within its borders and strong abroad."
Last December, the American forces executed what it described as a "major assault" against Islamic State objectives in Syria, following an ambush resulted in the deaths of two American soldiers and a civilian linguist in Palmyra.
The United Nations reports Daesh still boasts roughly 5-7 thousand fighters in both countries.